BDBM50089228 CHEMBL3577873

SMILES: CCNC(=O)N1CCC(CC1)Nc1ncc2ccc(=O)n(C(C)C)c2n1

InChI Key: InChIKey=YTNDEFNPJUZDTP-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50089228 (CHEMBL3577873) Show SMILES CCNC(=O)N1CCC(CC1)Nc1ncc2ccc(=O)n(C(C)C)c2n1 Show InChI InChI=1S/C18H26N6O2/c1-4-19-18(26)23-9-7-14(8-10-23)21-17-20-11-13-5-6-15(25)24(12(2)3)16(13)22-17/h5-6,11-12,14H,4,7-10H2,1-3H3,(H,19,26)(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assay				ACS Med Chem Lett 6: 413-8 (2015) Article DOI: 10.1021/ml500474d BindingDB Entry DOI: 10.7270/Q2KH0Q2N
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50089228 (CHEMBL3577873) Show SMILES CCNC(=O)N1CCC(CC1)Nc1ncc2ccc(=O)n(C(C)C)c2n1 Show InChI InChI=1S/C18H26N6O2/c1-4-19-18(26)23-9-7-14(8-10-23)21-17-20-11-13-5-6-15(25)24(12(2)3)16(13)22-17/h5-6,11-12,14H,4,7-10H2,1-3H3,(H,19,26)(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assay				ACS Med Chem Lett 6: 413-8 (2015) Article DOI: 10.1021/ml500474d BindingDB Entry DOI: 10.7270/Q2KH0Q2N
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50089228 (CHEMBL3577873) Show SMILES CCNC(=O)N1CCC(CC1)Nc1ncc2ccc(=O)n(C(C)C)c2n1 Show InChI InChI=1S/C18H26N6O2/c1-4-19-18(26)23-9-7-14(8-10-23)21-17-20-11-13-5-6-15(25)24(12(2)3)16(13)22-17/h5-6,11-12,14H,4,7-10H2,1-3H3,(H,19,26)(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK2 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assay				ACS Med Chem Lett 6: 413-8 (2015) Article DOI: 10.1021/ml500474d BindingDB Entry DOI: 10.7270/Q2KH0Q2N
					More data for this Ligand-Target Pair
MAP kinase p38 (Homo sapiens (Human))	BDBM50089228 (CHEMBL3577873) Show SMILES CCNC(=O)N1CCC(CC1)Nc1ncc2ccc(=O)n(C(C)C)c2n1 Show InChI InChI=1S/C18H26N6O2/c1-4-19-18(26)23-9-7-14(8-10-23)21-17-20-11-13-5-6-15(25)24(12(2)3)16(13)22-17/h5-6,11-12,14H,4,7-10H2,1-3H3,(H,19,26)(H,20,21,22)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of p38 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assay				ACS Med Chem Lett 6: 413-8 (2015) Article DOI: 10.1021/ml500474d BindingDB Entry DOI: 10.7270/Q2KH0Q2N
					More data for this Ligand-Target Pair