BDBM50089295 1-(5-(4-nitrophenoxy)pentyl)pyrrolidine::1-[5-(4-Nitro-phenoxy)-pentyl]-pyrrolidine::1-[5-(4-Nitro-phenoxy)-pentyl]-pyrrolidine(UCL1972)::CHEMBL289855::UCL-1972

SMILES: [O-][N+](=O)c1ccc(OCCCCCN2CCCC2)cc1

InChI Key: InChIKey=ITOJPDNONZGUKB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (GUINEA PIG)	BDBM50089295 (1-(5-(4-nitrophenoxy)pentyl)pyrrolidine | 1-[5-(4-...) Show SMILES [O-][N+](=O)c1ccc(OCCCCCN2CCCC2)cc1 Show InChI InChI=1S/C15H22N2O3/c18-17(19)14-6-8-15(9-7-14)20-13-5-1-2-10-16-11-3-4-12-16/h6-9H,1-5,10-13H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The James Black Foundation Curated by ChEMBL					Assay Description In vitro binding affinity of the compound towards histamine H3 receptor was determined in guinea-pig cerebral cortex using [3H]-(R)-alpha-methylhista...				J Med Chem 43: 2362-70 (2000) BindingDB Entry DOI: 10.7270/Q2WS8SGF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50089295 (1-(5-(4-nitrophenoxy)pentyl)pyrrolidine | 1-[5-(4-...) Show SMILES [O-][N+](=O)c1ccc(OCCCCCN2CCCC2)cc1 Show InChI InChI=1S/C15H22N2O3/c18-17(19)14-6-8-15(9-7-14)20-13-5-1-2-10-16-11-3-4-12-16/h6-9H,1-5,10-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description In vivo binding affinity was determined by measuring the displacement curves of [125I]iodoproxyfan in human Histamine H3 receptor antagonist with rel...				J Med Chem 46: 1523-30 (2003) Article DOI: 10.1021/jm021084k BindingDB Entry DOI: 10.7270/Q2C24X5N
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50089295 (1-(5-(4-nitrophenoxy)pentyl)pyrrolidine | 1-[5-(4-...) Show SMILES [O-][N+](=O)c1ccc(OCCCCCN2CCCC2)cc1 Show InChI InChI=1S/C15H22N2O3/c18-17(19)14-6-8-15(9-7-14)20-13-5-1-2-10-16-11-3-4-12-16/h6-9H,1-5,10-13H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Binding affinity to rat histamine H3 receptor				Bioorg Med Chem Lett 19: 903-7 (2009) Article DOI: 10.1016/j.bmcl.2008.11.114 BindingDB Entry DOI: 10.7270/Q2X63MTD
					More data for this Ligand-Target Pair