BDBM50089565 CHEMBL3578221

SMILES: CC(Cn1nc(-c2ccc3[nH]ccc3c2)c2c(N)ncnc12)c1ccccc1

InChI Key: InChIKey=FIBSJIPNOBLFML-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50089565 (CHEMBL3578221) Show SMILES CC(Cn1nc(-c2ccc3[nH]ccc3c2)c2c(N)ncnc12)c1ccccc1 Show InChI InChI=1S/C22H20N6/c1-14(15-5-3-2-4-6-15)12-28-22-19(21(23)25-13-26-22)20(27-28)17-7-8-18-16(11-17)9-10-24-18/h2-11,13-14,24H,12H2,1H3,(H2,23,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...				J Med Chem 58: 4590-609 (2015) Article DOI: 10.1021/acs.jmedchem.5b00140 BindingDB Entry DOI: 10.7270/Q29025HZ
					More data for this Ligand-Target Pair