BDBM50089566 CHEMBL3578220

SMILES: CC(Cn1nc(-c2ccc(cc2)C(C)=O)c2c(N)ncnc12)c1ccccc1

InChI Key: InChIKey=HEZVWAPSTXWGIR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50089566 (CHEMBL3578220) Show SMILES CC(Cn1nc(-c2ccc(cc2)C(C)=O)c2c(N)ncnc12)c1ccccc1 Show InChI InChI=1S/C22H21N5O/c1-14(16-6-4-3-5-7-16)12-27-22-19(21(23)24-13-25-22)20(26-27)18-10-8-17(9-11-18)15(2)28/h3-11,13-14H,12H2,1-2H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...				J Med Chem 58: 4590-609 (2015) Article DOI: 10.1021/acs.jmedchem.5b00140 BindingDB Entry DOI: 10.7270/Q29025HZ
					More data for this Ligand-Target Pair