BDBM50089761 (R)-1-[2-(1H-Indol-3-yl)-2-oxo-acetyl]-piperidine-3-carboxylic acid benzyl-methyl-amide::CHEMBL28730

SMILES: CN(Cc1ccccc1)C(=O)[C@@H]1CCCN(C1)C(=O)C(=O)c1c[nH]c2ccccc12

InChI Key: InChIKey=OWTXLWRGHNAFHX-GOSISDBHSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-2/gamma-2 subunit (Homo sapiens (Human))	BDBM50089761 ((R)-1-[2-(1H-Indol-3-yl)-2-oxo-acetyl]-piperidine-...) Show SMILES CN(Cc1ccccc1)C(=O)[C@@H]1CCCN(C1)C(=O)C(=O)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H25N3O3/c1-26(15-17-8-3-2-4-9-17)23(29)18-10-7-13-27(16-18)24(30)22(28)20-14-25-21-12-6-5-11-19(20)21/h2-6,8-9,11-12,14,18,25H,7,10,13,15-16H2,1H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity evaluated by ability to displace [3H]Ro-151788 from recombinant human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 expr...				Bioorg Med Chem Lett 10: 1381-4 (2000) BindingDB Entry DOI: 10.7270/Q2KD1X5T
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50089761 ((R)-1-[2-(1H-Indol-3-yl)-2-oxo-acetyl]-piperidine-...) Show SMILES CN(Cc1ccccc1)C(=O)[C@@H]1CCCN(C1)C(=O)C(=O)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H25N3O3/c1-26(15-17-8-3-2-4-9-17)23(29)18-10-7-13-27(16-18)24(30)22(28)20-14-25-21-12-6-5-11-19(20)21/h2-6,8-9,11-12,14,18,25H,7,10,13,15-16H2,1H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity evaluated by ability to displace [3H]-Ro-15-1788 from recombinant human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 ex...				Bioorg Med Chem Lett 10: 1381-4 (2000) BindingDB Entry DOI: 10.7270/Q2KD1X5T
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50089761 ((R)-1-[2-(1H-Indol-3-yl)-2-oxo-acetyl]-piperidine-...) Show SMILES CN(Cc1ccccc1)C(=O)[C@@H]1CCCN(C1)C(=O)C(=O)c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H25N3O3/c1-26(15-17-8-3-2-4-9-17)23(29)18-10-7-13-27(16-18)24(30)22(28)20-14-25-21-12-6-5-11-19(20)21/h2-6,8-9,11-12,14,18,25H,7,10,13,15-16H2,1H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity evaluated by ability to displace [3H]Ro-151788 from recombinant human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expr...				Bioorg Med Chem Lett 10: 1381-4 (2000) BindingDB Entry DOI: 10.7270/Q2KD1X5T
					More data for this Ligand-Target Pair