BDBM50089777 CHEMBL27621::Potassium; (5R,6S)-6-((R)-1-hydroxy-ethyl)-3-methoxy-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate
SMILES: COC1=C(N2[C@H](C1)[C@@H]([C@@H](C)O)C2=O)C([O-])=O
InChI Key: InChIKey=JQVSNQBXQNNKIW-WYDQCIBASA-M
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase (Enterobacter cloacae) | BDBM50089777 (CHEMBL27621 | Potassium; (5R,6S)-6-((R)-1-hydroxy-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Munich Curated by ChEMBL | Assay Description Beta-Lactamase inhibition activity after 15 min of preincubation with the enzyme isolated from Enterobacter cloacae | Bioorg Med Chem Lett 10: 1389-91 (2000) BindingDB Entry DOI: 10.7270/Q2FN15GX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (TEM-1) (Escherichia coli) | BDBM50089777 (CHEMBL27621 | Potassium; (5R,6S)-6-((R)-1-hydroxy-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Munich Curated by ChEMBL | Assay Description Beta-Lactamase inhibition activity after 15 min of preincubation with the enzyme isolated from Escherichia coli 205 TEM | Bioorg Med Chem Lett 10: 1389-91 (2000) BindingDB Entry DOI: 10.7270/Q2FN15GX | |||||||||||
More data for this Ligand-Target Pair |