BDBM50090062 1-(3,4-Dichloro-phenyl)-6-methyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL93153

SMILES: CC1N=C(N)N=C(N)N1c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=ZEOIMTZUCPVMBV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant KICB1 (Plasmodium falciparum)	BDBM50090062 (1-(3,4-Dichloro-phenyl)-6-methyl-1,6-dihydro-[1,3,...) Show SMILES CC1N=C(N)N=C(N)N1c1ccc(Cl)c(Cl)c1 |t:2,5| Show InChI InChI=1S/C10H11Cl2N5/c1-5-15-9(13)16-10(14)17(5)6-2-3-7(11)8(12)4-6/h2-5H,1H3,(H4,13,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Genetic Engineering and Biotechnology Curated by ChEMBL					Assay Description Evaluated for inhibition constant (Ki wt) against Wild-type dihydrofolate reductase of Plasmodium falciparum				J Med Chem 43: 2738-44 (2000) BindingDB Entry DOI: 10.7270/Q2P55MRR
					More data for this Ligand-Target Pair
Dihydrofolate reductase (A16V+S108T) (Plasmodium falciparum)	BDBM50090062 (1-(3,4-Dichloro-phenyl)-6-methyl-1,6-dihydro-[1,3,...) Show SMILES CC1N=C(N)N=C(N)N1c1ccc(Cl)c(Cl)c1 |t:2,5| Show InChI InChI=1S/C10H11Cl2N5/c1-5-15-9(13)16-10(14)17(5)6-2-3-7(11)8(12)4-6/h2-5H,1H3,(H4,13,14,15,16)	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Genetic Engineering and Biotechnology Curated by ChEMBL					Assay Description Inhibition constant (Ki mut) against A16V+S108T Mutant DHFRs of Plasmodium falciparum				J Med Chem 43: 2738-44 (2000) BindingDB Entry DOI: 10.7270/Q2P55MRR
					More data for this Ligand-Target Pair