BDBM50090323 CHEMBL289916::N-[3-(3',4',5',6'-Tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-propyl]-2,2-di-p-tolyl-acetamide

SMILES: Cc1ccc(cc1)C(C(=O)NCCCN1CCC(CC1)c1ccccn1)c1ccc(C)cc1

InChI Key: InChIKey=DQQUWTIATKHALF-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50090323 (CHEMBL289916 | N-[3-(3',4',5',6'-Tetrahydro-2'H-[2...) Show SMILES Cc1ccc(cc1)C(C(=O)NCCCN1CCC(CC1)c1ccccn1)c1ccc(C)cc1 Show InChI InChI=1S/C29H35N3O/c1-22-7-11-25(12-8-22)28(26-13-9-23(2)10-14-26)29(33)31-18-5-19-32-20-15-24(16-21-32)27-6-3-4-17-30-27/h3-4,6-14,17,24,28H,5,15-16,18-21H2,1-2H3,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-HEAT to cloned human alpha-1A adrenergic receptor.				Bioorg Med Chem Lett 10: 1621-4 (2000) BindingDB Entry DOI: 10.7270/Q27W6BDJ
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50090323 (CHEMBL289916 | N-[3-(3',4',5',6'-Tetrahydro-2'H-[2...) Show SMILES Cc1ccc(cc1)C(C(=O)NCCCN1CCC(CC1)c1ccccn1)c1ccc(C)cc1 Show InChI InChI=1S/C29H35N3O/c1-22-7-11-25(12-8-22)28(26-13-9-23(2)10-14-26)29(33)31-18-5-19-32-20-15-24(16-21-32)27-6-3-4-17-30-27/h3-4,6-14,17,24,28H,5,15-16,18-21H2,1-2H3,(H,31,33)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-HEAT to cloned human alpha-1B adrenergic receptor.				Bioorg Med Chem Lett 10: 1621-4 (2000) BindingDB Entry DOI: 10.7270/Q27W6BDJ
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50090323 (CHEMBL289916 | N-[3-(3',4',5',6'-Tetrahydro-2'H-[2...) Show SMILES Cc1ccc(cc1)C(C(=O)NCCCN1CCC(CC1)c1ccccn1)c1ccc(C)cc1 Show InChI InChI=1S/C29H35N3O/c1-22-7-11-25(12-8-22)28(26-13-9-23(2)10-14-26)29(33)31-18-5-19-32-20-15-24(16-21-32)27-6-3-4-17-30-27/h3-4,6-14,17,24,28H,5,15-16,18-21H2,1-2H3,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-HEAT to cloned human alpha-1D adrenergic receptor.				Bioorg Med Chem Lett 10: 1621-4 (2000) BindingDB Entry DOI: 10.7270/Q27W6BDJ
					More data for this Ligand-Target Pair