BDBM50090410 4-[Methyl-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-amino]-2-thiophen-2-yl-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL42547::ethyl 4-(methyl(3-methyl-2,5-dioxo-2H-pyrrol-1(5H)-yl)amino)-2-(thiophen-2-yl)pyrimidine-5-carboxylate

SMILES: CCOC(=O)c1cnc(nc1N(C)N1C(=O)C=C(C)C1=O)-c1cccs1

InChI Key: InChIKey=YZVLYVMNCAIILW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene c-JUN/protein c-fos (Homo sapiens (Human))	BDBM50090410 (4-[Methyl-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1...) Show SMILES CCOC(=O)c1cnc(nc1N(C)N1C(=O)C=C(C)C1=O)-c1cccs1 |t:17| Show InChI InChI=1S/C17H16N4O4S/c1-4-25-17(24)11-9-18-14(12-6-5-7-26-12)19-15(11)20(3)21-13(22)8-10(2)16(21)23/h5-9H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair