BDBM50090412 4-(2,5-Dioxo-3-phenyl-2,5-dihydro-pyrrol-1-ylamino)-2-trifluoromethyl-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL290656::ethyl 4-(2,5-dioxo-3-phenyl-2H-pyrrol-1(5H)-ylamino)-2-(trifluoromethyl)pyrimidine-5-carboxylate

SMILES: CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C1=O)c1ccccc1)C(F)(F)F

InChI Key: InChIKey=LCSVPHQXHLYQJW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene c-JUN/protein c-fos (Homo sapiens (Human))	BDBM50090412 (4-(2,5-Dioxo-3-phenyl-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C1=O)c1ccccc1)C(F)(F)F |c:16| Show InChI InChI=1S/C18H13F3N4O4/c1-2-29-16(28)12-9-22-17(18(19,20)21)23-14(12)24-25-13(26)8-11(15(25)27)10-6-4-3-5-7-10/h3-9H,2H2,1H3,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair