BDBM50090415 4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino)-2-phenylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL46509::ethyl 4-(3-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-ylamino)-2-(phenylthio)pyrimidine-5-carboxylate

SMILES: CCOC(=O)c1cnc(Sc2ccccc2)nc1NN1C(=O)C=C(C)C1=O

InChI Key: InChIKey=KBGATAWDHCZFQR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene c-JUN/protein c-fos (Homo sapiens (Human))	BDBM50090415 (4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...) Show SMILES CCOC(=O)c1cnc(Sc2ccccc2)nc1NN1C(=O)C=C(C)C1=O |t:24| Show InChI InChI=1S/C18H16N4O4S/c1-3-26-17(25)13-10-19-18(27-12-7-5-4-6-8-12)20-15(13)21-22-14(23)9-11(2)16(22)24/h4-10H,3H2,1-2H3,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair