BDBM50090416 2-Ethyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino)-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL43606::ethyl 2-ethyl-4-(3-methyl-2,5-dioxo-2H-pyrrol-1(5H)-ylamino)pyrimidine-5-carboxylate

SMILES: CCOC(=O)c1cnc(CC)nc1NN1C(=O)C=C(C)C1=O

InChI Key: InChIKey=CSRCUYXATBIFPU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene c-JUN/protein c-fos (Homo sapiens (Human))	BDBM50090416 (2-Ethyl-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1...) Show SMILES CCOC(=O)c1cnc(CC)nc1NN1C(=O)C=C(C)C1=O |t:18| Show InChI InChI=1S/C14H16N4O4/c1-4-10-15-7-9(14(21)22-5-2)12(16-10)17-18-11(19)6-8(3)13(18)20/h6-7H,4-5H2,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair