BDBM50090419 4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-ylamino)-2-trifluoromethyl-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL42687::ethyl 4-(2,5-dioxo-2H-pyrrol-1(5H)-ylamino)-2-(trifluoromethyl)pyrimidine-5-carboxylate

SMILES: CCOC(=O)c1cnc(nc1NN1C(=O)C=CC1=O)C(F)(F)F

InChI Key: InChIKey=CFZMCFDABIANIV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene c-JUN/protein c-fos (Homo sapiens (Human))	BDBM50090419 (4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-ylamino)-2-trifl...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=CC1=O)C(F)(F)F |c:16| Show InChI InChI=1S/C12H9F3N4O4/c1-2-23-10(22)6-5-16-11(12(13,14)15)17-9(6)18-19-7(20)3-4-8(19)21/h3-5H,2H2,1H3,(H,16,17,18)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair