BDBM50090439 2-Benzo[b]thiophen-2-yl-4-(3-methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino)-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL43199::ethyl 2-(benzo[b]thiophen-2-yl)-4-(3-methyl-2,5-dioxo-2H-pyrrol-1(5H)-ylamino)pyrimidine-5-carboxylate

SMILES: CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cc2ccccc2s1

InChI Key: InChIKey=DHUYKFJRTOWJRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene c-JUN/protein c-fos (Homo sapiens (Human))	BDBM50090439 (2-Benzo[b]thiophen-2-yl-4-(3-methyl-2,5-dioxo-2,5-...) Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)-c1cc2ccccc2s1 |t:16| Show InChI InChI=1S/C20H16N4O4S/c1-3-28-20(27)13-10-21-18(15-9-12-6-4-5-7-14(12)29-15)22-17(13)23-24-16(25)8-11(2)19(24)26/h4-10H,3H2,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair