BDBM50090442 3-Methyl-1-[5-(2-methyl-2H-tetrazol-5-yl)-2-thiophen-2-yl-pyrimidin-4-ylamino]-pyrrole-2,5-dione::3-methyl-1-(5-(2-methyl-2H-tetrazol-5-yl)-2-(thiophen-2-yl)pyrimidin-4-ylamino)-1H-pyrrole-2,5-dione::CHEMBL43534

SMILES: CC1=CC(=O)N(Nc2nc(ncc2-c2nnn(C)n2)-c2cccs2)C1=O

InChI Key: InChIKey=WKVHCLGIAQDALT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene c-JUN/protein c-fos (Homo sapiens (Human))	BDBM50090442 (3-Methyl-1-[5-(2-methyl-2H-tetrazol-5-yl)-2-thioph...) Show SMILES CC1=CC(=O)N(Nc2nc(ncc2-c2nnn(C)n2)-c2cccs2)C1=O |t:1| Show InChI InChI=1S/C15H12N8O2S/c1-8-6-11(24)23(15(8)25)20-12-9(13-18-21-22(2)19-13)7-16-14(17-12)10-4-3-5-26-10/h3-7H,1-2H3,(H,16,17,20)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair