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BDBM50090450 3-Methyl-1-[5-(5-methyl-[1,3,4]oxadiazol-2-yl)-2-thiophen-2-yl-pyrimidin-4-ylamino]-pyrrole-2,5-dione::3-methyl-1-(5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-(thiophen-2-yl)pyrimidin-4-ylamino)-1H-pyrrole-2,5-dione::CHEMBL296695

SMILES: CC1=CC(=O)N(Nc2nc(ncc2-c2nnc(C)o2)-c2cccs2)C1=O

InChI Key: InChIKey=CWMSEWLBVPSYON-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090450   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene c-JUN/protein c-fos


(Homo sapiens (Human))
BDBM50090450
PNG
(3-Methyl-1-[5-(5-methyl-[1,3,4]oxadiazol-2-yl)-2-t...)
Show SMILES CC1=CC(=O)N(Nc2nc(ncc2-c2nnc(C)o2)-c2cccs2)C1=O |t:1|
Show InChI InChI=1S/C16H12N6O3S/c1-8-6-12(23)22(16(8)24)21-13-10(15-20-19-9(2)25-15)7-17-14(18-13)11-4-3-5-26-11/h3-7H,1-2H3,(H,17,18,21)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 300n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells


Bioorg Med Chem Lett 10: 1645-8 (2000)


BindingDB Entry DOI: 10.7270/Q2F190XH
More data for this
Ligand-Target Pair