BDBM50090516 5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL49826
SMILES: CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)C(C)(C)C
InChI Key: InChIKey=PWWNBIOVLXARNT-OAHLLOKOSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50090516 (5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50090516 (5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp. Curated by ChEMBL | Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT | |||||||||||
More data for this Ligand-Target Pair |