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BDBM50090600 2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-N-pyrimidin-4-yl-acetamide::CHEMBL298374

SMILES: Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(CC(=O)Nc2ccncn2)C(=O)C1

InChI Key: InChIKey=GFCOASLPAVORJU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090600   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50090600
PNG
(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Show SMILES Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(CC(=O)Nc2ccncn2)C(=O)C1
Show InChI InChI=1S/C18H16ClN5O4S2/c19-13-2-1-12-7-18(29-14(12)8-13)30(27,28)24-6-5-23(17(26)10-24)9-16(25)22-15-3-4-20-11-21-15/h1-4,7-8,11H,5-6,9-10H2,(H,20,21,22,25)
PDB
MMDB

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PubMed
97n/an/an/an/an/an/an/an/a



Aventis Pharmaceuticals

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibitory activity against Coagulation factor X


Bioorg Med Chem Lett 10: 1737-9 (2000)


BindingDB Entry DOI: 10.7270/Q23777Z2
More data for this
Ligand-Target Pair