new BindingDB logo
myBDB logout

BDBM50090601 2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-N-phenyl-acetamide::CHEMBL296681

SMILES: Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(CC(=O)Nc2ccccc2)C(=O)C1

InChI Key: InChIKey=DRSWLWRQTBEPCM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090601   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50090601
PNG
(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Show SMILES Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(CC(=O)Nc2ccccc2)C(=O)C1
Show InChI InChI=1S/C20H18ClN3O4S2/c21-15-7-6-14-10-20(29-17(14)11-15)30(27,28)24-9-8-23(19(26)13-24)12-18(25)22-16-4-2-1-3-5-16/h1-7,10-11H,8-9,12-13H2,(H,22,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
>1.20E+3n/an/an/an/an/an/an/an/a



Aventis Pharmaceuticals

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibitory activity against Coagulation factor X


Bioorg Med Chem Lett 10: 1737-9 (2000)


BindingDB Entry DOI: 10.7270/Q23777Z2
More data for this
Ligand-Target Pair