BDBM50090603 CHEMBL295515::N-[2-(2-Amino-thiazol-4-yl)-ethyl]-2-[4-(6-chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-acetamide

SMILES: Nc1nc(CCNC(=O)CN2CCN(CC2=O)S(=O)(=O)c2cc3ccc(Cl)cc3s2)cs1

InChI Key: InChIKey=YEEFWWDMOPQODK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50090603 (CHEMBL295515 | N-[2-(2-Amino-thiazol-4-yl)-ethyl]-...) Show SMILES Nc1nc(CCNC(=O)CN2CCN(CC2=O)S(=O)(=O)c2cc3ccc(Cl)cc3s2)cs1 Show InChI InChI=1S/C19H20ClN5O4S3/c20-13-2-1-12-7-18(31-15(12)8-13)32(28,29)25-6-5-24(17(27)10-25)9-16(26)22-4-3-14-11-30-19(21)23-14/h1-2,7-8,11H,3-6,9-10H2,(H2,21,23)(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 10: 1737-9 (2000) BindingDB Entry DOI: 10.7270/Q23777Z2
					More data for this Ligand-Target Pair