BDBM50090610 2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-N-pyridin-3-yl-acetamide::CHEMBL298749

SMILES: Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(CC(=O)Nc2cccnc2)C(=O)C1

InChI Key: InChIKey=IBGHDRAHALYASH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50090610 (2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...) Show SMILES Clc1ccc2cc(sc2c1)S(=O)(=O)N1CCN(CC(=O)Nc2cccnc2)C(=O)C1 Show InChI InChI=1S/C19H17ClN4O4S2/c20-14-4-3-13-8-19(29-16(13)9-14)30(27,28)24-7-6-23(18(26)12-24)11-17(25)22-15-2-1-5-21-10-15/h1-5,8-10H,6-7,11-12H2,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 10: 1737-9 (2000) BindingDB Entry DOI: 10.7270/Q23777Z2
					More data for this Ligand-Target Pair