BDBM50090615 2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-N-[2-(4-methyl-thiazol-5-yl)-ethyl]-acetamide::CHEMBL296218

SMILES: Cc1ncsc1CCNC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cc2ccc(Cl)cc2s1

InChI Key: InChIKey=HDXMCPUBYMWVNU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50090615 (2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...) Show SMILES Cc1ncsc1CCNC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cc2ccc(Cl)cc2s1 Show InChI InChI=1S/C20H21ClN4O4S3/c1-13-16(30-12-23-13)4-5-22-18(26)10-24-6-7-25(11-19(24)27)32(28,29)20-8-14-2-3-15(21)9-17(14)31-20/h2-3,8-9,12H,4-7,10-11H2,1H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 10: 1737-9 (2000) BindingDB Entry DOI: 10.7270/Q23777Z2
					More data for this Ligand-Target Pair