BDBM50090636 (2Z,6E)-3-(butan-2-yl)-7,11-dimethyldodeca-2,6,10-trien-1-yl (phosphonatooxy)phosphonate::3-substituted farnesyl diphosphate analogue

SMILES: [#6]-[#6]-[#6](-[#6])-[#6](\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]/[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O

InChI Key: InChIKey=YMTDZEGWTFXVOA-RIUVRQHDSA-K

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50090636 ((2Z,6E)-3-(butan-2-yl)-7,11-dimethyldodeca-2,6,10-...) Show SMILES [#6]-[#6]-[#6](-[#6])-[#6](\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]/[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O Show InChI InChI=1S/C18H34O7P2/c1-6-17(5)18(12-8-11-16(4)10-7-9-15(2)3)13-14-24-27(22,23)25-26(19,20)21/h9,11,13,17H,6-8,10,12,14H2,1-5H3,(H,22,23)(H2,19,20,21)/p-3/b16-11+,18-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirus				Bioorg Med Chem Lett 10: 1763-6 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66KR
					More data for this Ligand-Target Pair