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SMILES: [#6]-[#6](-[#6])-[#6](\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]/[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O

InChI Key: InChIKey=DILCDDZDVRXNSW-BSTPEVQJSA-K

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090639   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50090639
PNG
((2Z,6E)-7,11-dimethyl-3-(propan-2-yl)dodeca-2,6,10...)
Show SMILES [#6]-[#6](-[#6])-[#6](\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]/[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O
Show InChI InChI=1S/C17H32O7P2/c1-14(2)8-6-9-16(5)10-7-11-17(15(3)4)12-13-23-26(21,22)24-25(18,19)20/h8,10,12,15H,6-7,9,11,13H2,1-5H3,(H,21,22)(H2,18,19,20)/p-3/b16-10+,17-12-
PDB
MMDB

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Similars
PubMed
n/an/a 35n/an/an/an/an/an/a



Wayne State University

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirus

Bioorg Med Chem Lett 10: 1763-6 (2000)


BindingDB Entry DOI: 10.7270/Q2BZ66KR
More data for this
Ligand-Target Pair