BDBM50090641 (2Z,6E)-3-(2,2-dimethylpropyl)-7,11-dimethyldodeca-2,6,10-trien-1-yl (phosphonatooxy)phosphonate::3-substituted farnesyl diphosphate analogue

SMILES: [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]C([#6])([#6])[#6])=[#6]\[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O

InChI Key: InChIKey=UGDXEILKWUZGPO-JAFZKPNWSA-K

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50090641 ((2Z,6E)-3-(2,2-dimethylpropyl)-7,11-dimethyldodeca...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]C([#6])([#6])[#6])=[#6]\[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O Show InChI InChI=1S/C19H36O7P2/c1-16(2)9-7-10-17(3)11-8-12-18(15-19(4,5)6)13-14-25-28(23,24)26-27(20,21)22/h9,11,13H,7-8,10,12,14-15H2,1-6H3,(H,23,24)(H2,20,21,22)/p-3/b17-11+,18-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirus				Bioorg Med Chem Lett 10: 1763-6 (2000) BindingDB Entry DOI: 10.7270/Q2BZ66KR
					More data for this Ligand-Target Pair