BDBM50090710 4-(7-Methyl-2-phenyl-[1,8]naphthyridin-4-yl)-piperazine-1-carboxylic acid ethyl ester::CHEMBL97663

SMILES: CCOC(=O)N1CCN(CC1)c1cc(nc2nc(C)ccc12)-c1ccccc1

InChI Key: InChIKey=XNJLKQQDQSMCOC-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A1 receptor (BOVINE)	BDBM50090710 (4-(7-Methyl-2-phenyl-[1,8]naphthyridin-4-yl)-piper...) Show SMILES CCOC(=O)N1CCN(CC1)c1cc(nc2nc(C)ccc12)-c1ccccc1 Show InChI InChI=1S/C22H24N4O2/c1-3-28-22(27)26-13-11-25(12-14-26)20-15-19(17-7-5-4-6-8-17)24-21-18(20)10-9-16(2)23-21/h4-10,15H,3,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranes				J Med Chem 43: 2814-23 (2000) BindingDB Entry DOI: 10.7270/Q21R6R6K
					More data for this Ligand-Target Pair
Adenosine receptor A2a and A3 (Rattus norvegicus)	BDBM50090710 (4-(7-Methyl-2-phenyl-[1,8]naphthyridin-4-yl)-piper...) Show SMILES CCOC(=O)N1CCN(CC1)c1cc(nc2nc(C)ccc12)-c1ccccc1 Show InChI InChI=1S/C22H24N4O2/c1-3-28-22(27)26-13-11-25(12-14-26)20-15-19(17-7-5-4-6-8-17)24-21-18(20)10-9-16(2)23-21/h4-10,15H,3,11-14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from rat testis membranes				J Med Chem 43: 2814-23 (2000) BindingDB Entry DOI: 10.7270/Q21R6R6K
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50090710 (4-(7-Methyl-2-phenyl-[1,8]naphthyridin-4-yl)-piper...) Show SMILES CCOC(=O)N1CCN(CC1)c1cc(nc2nc(C)ccc12)-c1ccccc1 Show InChI InChI=1S/C22H24N4O2/c1-3-28-22(27)26-13-11-25(12-14-26)20-15-19(17-7-5-4-6-8-17)24-21-18(20)10-9-16(2)23-21/h4-10,15H,3,11-14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Ability to displace the specific binding of [3H]-CGS- to adenosine A2A receptor form bovine brain striatal membranes				J Med Chem 43: 2814-23 (2000) BindingDB Entry DOI: 10.7270/Q21R6R6K
					More data for this Ligand-Target Pair