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BDBM50090907 CHEBI:66041::CHEMBL444160

SMILES: Oc1ccc2c3ccnc4ccc(=O)n(c2c1)c34

InChI Key: InChIKey=JHPIJMUNSMWWAA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090907   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50090907
PNG
(CHEBI:66041 | CHEMBL444160)
Show SMILES Oc1ccc2c3ccnc4ccc(=O)n(c2c1)c34
Show InChI InChI=1S/C14H8N2O2/c17-8-1-2-9-10-5-6-15-11-3-4-13(18)16(14(10)11)12(9)7-8/h1-7,17H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.80E+3n/an/an/an/an/an/a



Chiba University

Curated by ChEMBL


Assay Description
Activation of GSK-3beta in HEK293 cells assessed as suppression of TCF/beta-catenin transcriptional activity after 24 hrs by SuperTOPFlash reporter g...


J Nat Prod 78: 1139-46 (2015)


Article DOI: 10.1021/acs.jnatprod.5b00153
BindingDB Entry DOI: 10.7270/Q2P270VC
More data for this
Ligand-Target Pair