BDBM50090968 CHEMBL3582035
SMILES: Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1
InChI Key: InChIKey=AEXYDYPBGQQOMN-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage-stimulating protein receptor (Homo sapiens (Human)) | BDBM50090968 (CHEMBL3582035) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemRF Laboratories Curated by ChEMBL | Assay Description Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISA | Bioorg Med Chem Lett 25: 2527-31 (2015) Article DOI: 10.1016/j.bmcl.2015.04.056 BindingDB Entry DOI: 10.7270/Q21C1ZMR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50090968 (CHEMBL3582035) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemRF Laboratories Curated by ChEMBL | Assay Description Inhibition of phosphorylation of c-Met in human MKN45 cells | Bioorg Med Chem Lett 25: 2527-31 (2015) Article DOI: 10.1016/j.bmcl.2015.04.056 BindingDB Entry DOI: 10.7270/Q21C1ZMR | |||||||||||
More data for this Ligand-Target Pair |