BDBM50091043 CHEMBL3582115

SMILES: Cc1cnn(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCc12

InChI Key: InChIKey=ARSOCJAZLCXHOY-KEVXWDJXSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091043   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50091043 (CHEMBL3582115) Show SMILES Cc1cnn(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCc12 |(2.53,-4.52,;3.46,-3.71,;4.96,-4.03,;5.74,-2.7,;4.71,-1.55,;4.96,-.35,;3.32,-2.19,;2,-1.39,;.66,-2.11,;-.68,-1.39,;-.68,.15,;-2,.92,;-3.35,.15,;-4.41,-.49,;-3.32,1.38,;-3.35,-1.39,;-4.41,-2.03,;-2,-2.11,;-.91,-2.69,;-3.08,-2.71,;.66,.92,;.98,2.43,;2.53,2.6,;3.17,1.19,;2,.15,)| Show InChI InChI=1S/C30H58O10/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-38-21-23(37-2)22-39-30(36)40-29-26(33)24(20-31)25(32)27(34)28(29)35/h23-29,31-35H,3-22H2,1-2H3/t23-,24-,25?,26?,27?,28?,29?/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-dexamethasone from cytosolic fraction of human recombinant glucocorticoid receptor by scintillation counting analysis				J Med Chem 58: 4918-26 (2015) Article DOI: 10.1021/jm501758q BindingDB Entry DOI: 10.7270/Q2WM1G4V
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50091043 (CHEMBL3582115) Show SMILES Cc1cnn(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCc12 |(2.53,-4.52,;3.46,-3.71,;4.96,-4.03,;5.74,-2.7,;4.71,-1.55,;4.96,-.35,;3.32,-2.19,;2,-1.39,;.66,-2.11,;-.68,-1.39,;-.68,.15,;-2,.92,;-3.35,.15,;-4.41,-.49,;-3.32,1.38,;-3.35,-1.39,;-4.41,-2.03,;-2,-2.11,;-.91,-2.69,;-3.08,-2.71,;.66,.92,;.98,2.43,;2.53,2.6,;3.17,1.19,;2,.15,)| Show InChI InChI=1S/C30H58O10/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-38-21-23(37-2)22-39-30(36)40-29-26(33)24(20-31)25(32)27(34)28(29)35/h23-29,31-35H,3-22H2,1-2H3/t23-,24-,25?,26?,27?,28?,29?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-progesterone from cytosolic fraction of human recombinant progesterone-B receptor by scintillation counting analysis				J Med Chem 58: 4918-26 (2015) Article DOI: 10.1021/jm501758q BindingDB Entry DOI: 10.7270/Q2WM1G4V
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50091043 (CHEMBL3582115) Show SMILES Cc1cnn(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCc12 |(2.53,-4.52,;3.46,-3.71,;4.96,-4.03,;5.74,-2.7,;4.71,-1.55,;4.96,-.35,;3.32,-2.19,;2,-1.39,;.66,-2.11,;-.68,-1.39,;-.68,.15,;-2,.92,;-3.35,.15,;-4.41,-.49,;-3.32,1.38,;-3.35,-1.39,;-4.41,-2.03,;-2,-2.11,;-.91,-2.69,;-3.08,-2.71,;.66,.92,;.98,2.43,;2.53,2.6,;3.17,1.19,;2,.15,)| Show InChI InChI=1S/C30H58O10/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-38-21-23(37-2)22-39-30(36)40-29-26(33)24(20-31)25(32)27(34)28(29)35/h23-29,31-35H,3-22H2,1-2H3/t23-,24-,25?,26?,27?,28?,29?/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor transfected in CHOK1 cells assessed as inhibition of dexamethasone-induced receptor transcriptio...				J Med Chem 58: 4918-26 (2015) Article DOI: 10.1021/jm501758q BindingDB Entry DOI: 10.7270/Q2WM1G4V
					More data for this Ligand-Target Pair