BDBM50091103 4'-(4,5-Dimethyl-oxazol-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL106749

SMILES: Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nc(C)c(C)o2)c1C

InChI Key: InChIKey=OJUNZBGNMUTVGC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50091103 (4'-(4,5-Dimethyl-oxazol-2-yl)-biphenyl-2-sulfonic ...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nc(C)c(C)o2)c1C Show InChI InChI=1S/C22H21N3O4S/c1-13-14(2)24-29-21(13)25-30(26,27)20-8-6-5-7-19(20)17-9-11-18(12-10-17)22-23-15(3)16(4)28-22/h5-12,25H,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of Human Endothelin A receptor expressed in CHO Cells.				J Med Chem 43: 3111-7 (2000) BindingDB Entry DOI: 10.7270/Q2DF6QFM
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50091103 (4'-(4,5-Dimethyl-oxazol-2-yl)-biphenyl-2-sulfonic ...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nc(C)c(C)o2)c1C Show InChI InChI=1S/C22H21N3O4S/c1-13-14(2)24-29-21(13)25-30(26,27)20-8-6-5-7-19(20)17-9-11-18(12-10-17)22-23-15(3)16(4)28-22/h5-12,25H,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inihibition of Human Endothelin B receptor expressed in CHO Cells.				J Med Chem 43: 3111-7 (2000) BindingDB Entry DOI: 10.7270/Q2DF6QFM
					More data for this Ligand-Target Pair