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BDBM50091397 1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-pentan-1-one oxime; compound with but-2-enedioic acid (0.25M H2O)::CHEMBL113181

SMILES: CCCCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1

InChI Key: InChIKey=GNZCOOGORVEPLL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091397   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50091397
PNG
(1-{4-[3-(1H-Imidazol-4-yl)-propoxy]-phenyl}-pentan...)
Show SMILES CCCCC(N=O)c1ccc(OCCCc2cnc[nH]2)cc1
Show InChI InChI=1S/C17H23N3O2/c1-2-3-6-17(20-21)14-7-9-16(10-8-14)22-11-4-5-15-12-18-13-19-15/h7-10,12-13,17H,2-6,11H2,1H3,(H,18,19)
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Similars
PubMed
 4.90n/an/an/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.

J Med Chem 43: 3335-43 (2000)


BindingDB Entry DOI: 10.7270/Q2RR1XGV
More data for this
Ligand-Target Pair