BDBM50091401 4-[3-(4-Hydroxy-butyl)-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl]-2-iodo-benzonitrile::CHEMBL419767
SMILES: CC1(C)N(CCCCO)C(=S)N(C1=O)c1ccc(C#N)c(I)c1
InChI Key: InChIKey=COLBUQNTUDHMHF-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen Receptor (Rattus norvegicus (Rat)) | BDBM50091401 (4-[3-(4-Hydroxy-butyl)-4,4-dimethyl-5-oxo-2-thioxo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.708 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSC-Scientific Computing Ltd. Curated by ChEMBL | Assay Description Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventral prostate | J Med Chem 48: 917-25 (2005) Article DOI: 10.1021/jm0495879 BindingDB Entry DOI: 10.7270/Q2SJ1PBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50091401 (4-[3-(4-Hydroxy-butyl)-4,4-dimethyl-5-oxo-2-thioxo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Michigan Medical School Curated by ChEMBL | Assay Description Inhibitory constant against rat prostate cytosol androgen receptor using [3H]mibolerone | J Med Chem 43: 3344-7 (2000) BindingDB Entry DOI: 10.7270/Q2GQ6ZFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Rattus norvegicus (Rat)) | BDBM50091401 (4-[3-(4-Hydroxy-butyl)-4,4-dimethyl-5-oxo-2-thioxo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Michigan Medical School Curated by ChEMBL | Assay Description Inhibition of rat prostate cytosolic androgen receptor | Bioorg Med Chem Lett 14: 5285-8 (2004) Article DOI: 10.1016/j.bmcl.2004.08.031 BindingDB Entry DOI: 10.7270/Q29K4BZG | |||||||||||
More data for this Ligand-Target Pair |