BDBM50091444 Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-piperidin-1-yl]-pentyl}-amide::CHEMBL53819

SMILES: O=C(NCCCCCN1CCC(CC1)c1c[nH]c2ccccc12)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=ICGRBUBHSBWCDK-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091444 (Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...) Show SMILES O=C(NCCCCCN1CCC(CC1)c1c[nH]c2ccccc12)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C31H35N3O/c35-31(27-15-13-25(14-16-27)24-9-3-1-4-10-24)32-19-7-2-8-20-34-21-17-26(18-22-34)29-23-33-30-12-6-5-11-28(29)30/h1,3-6,9-16,23,26,33H,2,7-8,17-22H2,(H,32,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2				Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091444 (Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...) Show SMILES O=C(NCCCCCN1CCC(CC1)c1c[nH]c2ccccc12)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C31H35N3O/c35-31(27-15-13-25(14-16-27)24-9-3-1-4-10-24)32-19-7-2-8-20-34-21-17-26(18-22-34)29-23-33-30-12-6-5-11-28(29)30/h1,3-6,9-16,23,26,33H,2,7-8,17-22H2,(H,32,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against C-C chemokine receptor type 2				Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091444 (Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...) Show SMILES O=C(NCCCCCN1CCC(CC1)c1c[nH]c2ccccc12)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C31H35N3O/c35-31(27-15-13-25(14-16-27)24-9-3-1-4-10-24)32-19-7-2-8-20-34-21-17-26(18-22-34)29-23-33-30-12-6-5-11-28(29)30/h1,3-6,9-16,23,26,33H,2,7-8,17-22H2,(H,32,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor				Bioorg Med Chem Lett 18: 1450-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.072 BindingDB Entry DOI: 10.7270/Q26T0MC4
					More data for this Ligand-Target Pair