BDBM50091446 (E)-3-(4-Cyano-phenyl)-N-{5-[4-(1H-indol-3-yl)-piperidin-1-yl]-pentyl}-acrylamide::(E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-3-(4-cyanophenyl)acrylamide::CHEMBL53557

SMILES: O=C(NCCCCCN1CCC(CC1)c1c[nH]c2ccccc12)\C=C\c1ccc(cc1)C#N

InChI Key: InChIKey=XKGRJLFRTKBNGI-OUKQBFOZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091446 ((E)-3-(4-Cyano-phenyl)-N-{5-[4-(1H-indol-3-yl)-pip...) Show SMILES O=C(NCCCCCN1CCC(CC1)c1c[nH]c2ccccc12)\C=C\c1ccc(cc1)C#N Show InChI InChI=1S/C28H32N4O/c29-20-23-10-8-22(9-11-23)12-13-28(33)30-16-4-1-5-17-32-18-14-24(15-19-32)26-21-31-27-7-3-2-6-25(26)27/h2-3,6-13,21,24,31H,1,4-5,14-19H2,(H,30,33)/b13-12+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor				Bioorg Med Chem Lett 18: 1450-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.072 BindingDB Entry DOI: 10.7270/Q26T0MC4
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091446 ((E)-3-(4-Cyano-phenyl)-N-{5-[4-(1H-indol-3-yl)-pip...) Show SMILES O=C(NCCCCCN1CCC(CC1)c1c[nH]c2ccccc12)\C=C\c1ccc(cc1)C#N Show InChI InChI=1S/C28H32N4O/c29-20-23-10-8-22(9-11-23)12-13-28(33)30-16-4-1-5-17-32-18-14-24(15-19-32)26-21-31-27-7-3-2-6-25(26)27/h2-3,6-13,21,24,31H,1,4-5,14-19H2,(H,30,33)/b13-12+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against C-C chemokine receptor type 2				Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z
					More data for this Ligand-Target Pair