BDBM50091453 (E)-3-(3,4-Dichloro-phenyl)-N-{3-[4-(1H-indol-3-yl)-piperidin-1-yl]-propyl}-acrylamide::(E)-N-(3-(4-(1H-indol-3-yl)piperidin-1-yl)propyl)-3-(3,4-dichlorophenyl)acrylamide::CHEMBL297950::TCMDC-139332

SMILES: Clc1ccc(\C=C\C(=O)NCCCN2CCC(CC2)c2c[nH]c3ccccc23)cc1Cl

InChI Key: InChIKey=OWUZRSKHAOSPIO-VQHVLOKHSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091453 ((E)-3-(3,4-Dichloro-phenyl)-N-{3-[4-(1H-indol-3-yl...) Show SMILES Clc1ccc(\C=C\C(=O)NCCCN2CCC(CC2)c2c[nH]c3ccccc23)cc1Cl Show InChI InChI=1S/C25H27Cl2N3O/c26-22-8-6-18(16-23(22)27)7-9-25(31)28-12-3-13-30-14-10-19(11-15-30)21-17-29-24-5-2-1-4-20(21)24/h1-2,4-9,16-17,19,29H,3,10-15H2,(H,28,31)/b9-7+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor				Bioorg Med Chem Lett 18: 1450-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.072 BindingDB Entry DOI: 10.7270/Q26T0MC4
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091453 ((E)-3-(3,4-Dichloro-phenyl)-N-{3-[4-(1H-indol-3-yl...) Show SMILES Clc1ccc(\C=C\C(=O)NCCCN2CCC(CC2)c2c[nH]c3ccccc23)cc1Cl Show InChI InChI=1S/C25H27Cl2N3O/c26-22-8-6-18(16-23(22)27)7-9-25(31)28-12-3-13-30-14-10-19(11-15-30)21-17-29-24-5-2-1-4-20(21)24/h1-2,4-9,16-17,19,29H,3,10-15H2,(H,28,31)/b9-7+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against C-C chemokine receptor type 2				Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z
					More data for this Ligand-Target Pair