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BDBM50091457 (E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-2-methyl-1H-indol-3-yl)-piperidin-1-yl]-pentyl}-acrylamide::CHEMBL300455::TCMDC-139283

SMILES: Cc1[nH]c2ccc(O)cc2c1C1CCN(CCCCCNC(=O)\C=C\c2ccc(Cl)c(Cl)c2)CC1

InChI Key: InChIKey=LISWCGNYNKBWAV-UXBLZVDNSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091457   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50091457
PNG
((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-2-m...)
Show SMILES Cc1[nH]c2ccc(O)cc2c1C1CCN(CCCCCNC(=O)\C=C\c2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C28H33Cl2N3O2/c1-19-28(23-18-22(34)7-9-26(23)32-19)21-11-15-33(16-12-21)14-4-2-3-13-31-27(35)10-6-20-5-8-24(29)25(30)17-20/h5-10,17-18,21,32,34H,2-4,11-16H2,1H3,(H,31,35)/b10-6+
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 234n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity against C-C chemokine receptor type 2

Bioorg Med Chem Lett 10: 1803-6 (2000)


BindingDB Entry DOI: 10.7270/Q2H70F2Z
More data for this
Ligand-Target Pair