BDBM50091468 (E)-3-(4-Dimethylamino-phenyl)-N-{5-[4-(1H-indol-3-yl)-piperidin-1-yl]-pentyl}-acrylamide::(E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-3-(4-(dimethylamino)phenyl)acrylamide::CHEMBL49994

SMILES: CN(C)c1ccc(\C=C\C(=O)NCCCCCN2CCC(CC2)c2c[nH]c3ccccc23)cc1

InChI Key: InChIKey=HGEZURWKWAYCLS-NTCAYCPXSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091468 ((E)-3-(4-Dimethylamino-phenyl)-N-{5-[4-(1H-indol-3...) Show SMILES CN(C)c1ccc(\C=C\C(=O)NCCCCCN2CCC(CC2)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C29H38N4O/c1-32(2)25-13-10-23(11-14-25)12-15-29(34)30-18-6-3-7-19-33-20-16-24(17-21-33)27-22-31-28-9-5-4-8-26(27)28/h4-5,8-15,22,24,31H,3,6-7,16-21H2,1-2H3,(H,30,34)/b15-12+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor				Bioorg Med Chem Lett 18: 1450-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.072 BindingDB Entry DOI: 10.7270/Q26T0MC4
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091468 ((E)-3-(4-Dimethylamino-phenyl)-N-{5-[4-(1H-indol-3...) Show SMILES CN(C)c1ccc(\C=C\C(=O)NCCCCCN2CCC(CC2)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C29H38N4O/c1-32(2)25-13-10-23(11-14-25)12-15-29(34)30-18-6-3-7-19-33-20-16-24(17-21-33)27-22-31-28-9-5-4-8-26(27)28/h4-5,8-15,22,24,31H,3,6-7,16-21H2,1-2H3,(H,30,34)/b15-12+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against C-C chemokine receptor type 2				Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z
					More data for this Ligand-Target Pair