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SMILES: Cc1ccc(NC(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1Cl

InChI Key: InChIKey=UBUFVRJUGFJQSI-GUFHCOKKSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091598   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))		BDBM50091598
PNG
(CHEMBL3582349)
Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1Cl
Show InChI InChI=1S/C38H47N5O5/c1-38(2,3)41-36(47)32-24-42(22-26-18-28-13-16-48-37(28)39-21-26)14-15-43(32)23-30(44)19-29(17-25-9-5-4-6-10-25)35(46)40-34-31-12-8-7-11-27(31)20-33(34)45/h4-13,16,18,21,29-30,32-34,44-45H,14-15,17,19-20,22-24H2,1-3H3,(H,40,46)(H,41,47)/t29-,30+,32+,33-,34?/m1/s1
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MMDB

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Similars
Article
PubMed
 0.770n/an/an/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of carbonic anhydrase-2 (unknown origin) incubated for 15 mins prior to testing by stopped-flow CO2 hydration assay

ACS Med Chem Lett 6: 518-22 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00062
BindingDB Entry DOI: 10.7270/Q2GF0W8S
More data for this
Ligand-Target Pair