BDBM50091748 (S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbamoyl)-butyl]-3-{(S)-2-[(S)-5-guanidino-2-(2-{4-[(naphthalene-2-carbonyl)-amino]-phenyl}-acetylamino)-pentanoylamino]-propionylamino}-succinamic acid::CHEMBL294262
SMILES: CC[C@H](C)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1
InChI Key: InChIKey=UWAQSJWJCXAOOI-LPRIMMJDSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Atrial natriuretic peptide receptor (Homo sapiens (Human)) | BDBM50091748 ((S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbam...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of [125I]- ANP from the Atrial natriuretic peptide receptor A. | Bioorg Med Chem Lett 10: 1949-52 (2001) BindingDB Entry DOI: 10.7270/Q2BK1BKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Atrial natriuretic peptide receptor 3 (Homo sapiens (Human)) | BDBM50091748 ((S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of [125I]- ANP from the Atrial Natriuretic Peptide Clearance Receptor. | Bioorg Med Chem Lett 10: 1949-52 (2001) BindingDB Entry DOI: 10.7270/Q2BK1BKQ | |||||||||||
More data for this Ligand-Target Pair |