BDBM50091826 (S)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxaline::CHEMBL61695

SMILES: Clc1cc2NC[C@@H]3CNCCN3c2cc1Cl

InChI Key: InChIKey=DYCDNKQNLQYZCD-ZETCQYMHSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091826 ((S)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...) Show SMILES Clc1cc2NC[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [125I]-DOI as radioligand with membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091826 ((S)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...) Show SMILES Clc1cc2NC[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity using [3H]-mesulergine as radioligand with receptor membranes isolated from a CHO-k cell line expressing the human 5-hydroxytryptami...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50091826 ((S)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazin...) Show SMILES Clc1cc2NC[C@@H]3CNCCN3c2cc1Cl Show InChI InChI=1S/C11H13Cl2N3/c12-8-3-10-11(4-9(8)13)16-2-1-14-5-7(16)6-15-10/h3-4,7,14-15H,1-2,5-6H2/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Agonistic activity for 5-HT2c (5-HT2C) by measuring [3H]-inositol monophosphate fromation in CHO cells in which the human 5-HT2C receptor subtype was...				Bioorg Med Chem Lett 10: 1991-4 (2001) BindingDB Entry DOI: 10.7270/Q2Z89BMP
					More data for this Ligand-Target Pair