BDBM50091931 1-[5-tert-Butyl-2-(3-nitro-phenyl)-2H-pyrazol-3-yl]-3-(2,3-dichloro-phenyl)-urea::CHEMBL64041

SMILES: CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(n1)-c1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=KXQRNZIJVGMDMI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50091931 (1-[5-tert-Butyl-2-(3-nitro-phenyl)-2H-pyrazol-3-yl...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(n1)-c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C20H19Cl2N5O3/c1-20(2,3)16-11-17(24-19(28)23-15-9-5-8-14(21)18(15)22)26(25-16)12-6-4-7-13(10-12)27(29)30/h4-11H,1-3H3,(H2,23,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of mitogen-activated protein kinase p38 alpha 2				Bioorg Med Chem Lett 10: 2051-4 (2000) BindingDB Entry DOI: 10.7270/Q29K49GS
					More data for this Ligand-Target Pair