BDBM50091969 1-(5-Bromo-pyridin-2-yl)-3-((R)-1-phenyl-ethyl)-thiourea::CHEMBL432526::HI-511

SMILES: C[C@@H](NC(=S)Nc1ccc(Br)cn1)c1ccccc1

InChI Key: InChIKey=WMEZMEPKDSDHFN-SNVBAGLBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50091969 (1-(5-Bromo-pyridin-2-yl)-3-((R)-1-phenyl-ethyl)-th...) Show SMILES C[C@@H](NC(=S)Nc1ccc(Br)cn1)c1ccccc1 Show InChI InChI=1S/C14H14BrN3S/c1-10(11-5-3-2-4-6-11)17-14(19)18-13-8-7-12(15)9-16-13/h2-10H,1H3,(H2,16,17,18,19)/t10-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory activity against recombinant HIV-1 Reverse transcriptase using cell free RT inhibition assay				Bioorg Med Chem Lett 10: 2071-4 (2000) BindingDB Entry DOI: 10.7270/Q2668DQZ
					More data for this Ligand-Target Pair