BDBM50091970 1-((S)-1-Cyclohexyl-ethyl)-3-thiazol-2-yl-thiourea::CHEMBL434213::HI-513
SMILES: C[C@H](NC(=S)Nc1nccs1)C1CCCCC1
InChI Key: InChIKey=YMIPFHHBIUGWRO-VIFPVBQESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50091970 (1-((S)-1-Cyclohexyl-ethyl)-3-thiazol-2-yl-thiourea...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Binding affinity against HIV reverse transcriptase (Estimated Ki) | Bioorg Med Chem Lett 10: 2071-4 (2000) BindingDB Entry DOI: 10.7270/Q2668DQZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50091970 (1-((S)-1-Cyclohexyl-ethyl)-3-thiazol-2-yl-thiourea...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Compound was evaluated for its inhibitory activity against recombinant HIV-1 Reverse transcriptase using cell free RT inhibition assay | Bioorg Med Chem Lett 10: 2071-4 (2000) BindingDB Entry DOI: 10.7270/Q2668DQZ | |||||||||||
More data for this Ligand-Target Pair |