BDBM50092011 CHEMBL3582384

SMILES: Fc1cccc(c1)S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F

InChI Key: InChIKey=HBJGQDFVZLTVDA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50092011 (CHEMBL3582384) Show SMILES Fc1cccc(c1)S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F Show InChI InChI=1S/C20H11F3N4O2S/c21-14-2-1-3-15(9-14)30(28,29)27-18-7-6-17(22)16(19(18)23)5-4-12-8-13-11-25-26-20(13)24-10-12/h1-3,6-11,27H,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair