BindingDB PrimarySearch

BDBM50092015 (10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraene-11-thione::CHEMBL63262

SMILES: CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=S)c23

InChI Key: InChIKey=RVIJQMOQZFCSHL-LRDDRELGSA-N

Data: 13 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50092015
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity for Protein kinase C eta C1a domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C epsilon C1b domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C theta C1b domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C delta C1b domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C eta C1b domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	226	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C beta C1b domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	262	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C alpha C1a domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	288	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C gamma C1a domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity for Protein kinase C beta C1b domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C alpha C1b domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, eta (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C eta C1a domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C alpha C1a domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM50092015 ((10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]- PDBu from Protein kinase C epsilon C1a domain				Bioorg Med Chem Lett 10: 2087-90 (2000) BindingDB Entry DOI: 10.7270/Q22F7NZS
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair