BDBM50092042 3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one::CHEMBL67222

SMILES: Clc1ccc(CN2CCN(CC2)C2Cc3ccccc3NC2=O)cc1

InChI Key: InChIKey=NKJVFWPJNBYTCK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50092042 (3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-3,4-dihydro...) Show SMILES Clc1ccc(CN2CCN(CC2)C2Cc3ccccc3NC2=O)cc1 Show InChI InChI=1S/C20H22ClN3O/c21-17-7-5-15(6-8-17)14-23-9-11-24(12-10-23)19-13-16-3-1-2-4-18(16)22-20(19)25/h1-8,19H,9-14H2,(H,22,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity at human Dopamine receptor D4 by [3H]- YM 09151 displacement.				Bioorg Med Chem Lett 10: 2119-22 (2000) BindingDB Entry DOI: 10.7270/Q2SN0869
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50092042 (3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-3,4-dihydro...) Show SMILES Clc1ccc(CN2CCN(CC2)C2Cc3ccccc3NC2=O)cc1 Show InChI InChI=1S/C20H22ClN3O/c21-17-7-5-15(6-8-17)14-23-9-11-24(12-10-23)19-13-16-3-1-2-4-18(16)22-20(19)25/h1-8,19H,9-14H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Binding affinity at human Dopamine receptor D2 by [3H]- YM 09151 displacement.				Bioorg Med Chem Lett 10: 2119-22 (2000) BindingDB Entry DOI: 10.7270/Q2SN0869
					More data for this Ligand-Target Pair