BDBM50092052 1-Ethyl-3-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL302340
SMILES: CCN1c2ccccc2CCC(N2CCN(Cc3ccc(C)cc3)CC2)C1=O
InChI Key: InChIKey=IFFCYSLODLRHJM-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50092052 (1-Ethyl-3-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Binding affinity at human Dopamine receptor D2 by [3H]- YM 09151 displacement. | Bioorg Med Chem Lett 10: 2119-22 (2000) BindingDB Entry DOI: 10.7270/Q2SN0869 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50092052 (1-Ethyl-3-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,3...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation Curated by ChEMBL | Assay Description Binding affinity at human Dopamine receptor D4 by [3H]- YM 09151 displacement. | Bioorg Med Chem Lett 10: 2119-22 (2000) BindingDB Entry DOI: 10.7270/Q2SN0869 | |||||||||||
More data for this Ligand-Target Pair |