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SMILES: O=C1C(C(=O)C(=O)C(C1=O)c1cccc2ccccc12)c1ccccc1

InChI Key: InChIKey=VWKUJRNBECSYTE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092147   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Insulin receptor


(Homo sapiens (Human))		BDBM50092147
PNG
(2,5-Dihydroxy-3-naphthalen-1-yl-6-phenyl-[1,4]benz...)
Show SMILES O=C1C(C(=O)C(=O)C(C1=O)c1cccc2ccccc12)c1ccccc1 |(8.71,-2.51,;8.71,-4.05,;10.04,-4.82,;10.04,-6.37,;11.39,-7.14,;8.71,-7.14,;8.71,-8.68,;7.39,-6.37,;7.39,-4.82,;6.04,-4.05,;6.04,-7.14,;6.06,-8.68,;4.73,-9.45,;3.37,-8.68,;3.37,-7.14,;2.06,-6.38,;2.04,-4.85,;3.39,-4.08,;4.71,-4.85,;4.71,-6.38,;11.39,-4.05,;11.37,-2.53,;12.7,-1.75,;14.06,-2.53,;14.05,-4.08,;12.7,-4.84,)|
Show InChI InChI=1S/C22H14O4/c23-19-17(14-8-2-1-3-9-14)20(24)22(26)18(21(19)25)16-12-6-10-13-7-4-5-11-15(13)16/h1-12,17-18H
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KEGG

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PC cid
PC sid
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Similars
PubMed
n/an/an/an/a 6.00E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Activation of human insulin receptor tyrosine kinase (IRTK)

J Med Chem 43: 3487-94 (2000)


BindingDB Entry DOI: 10.7270/Q2NV9HHG
More data for this
Ligand-Target Pair