BDBM50092170 CHEMBL116372::N*8*,N*8*-Dipropyl-8,9-dihydro-7H-chromeno[6,5-d]thiazole-2,8-diamine

SMILES: CCCN(CCC)C1COc2ccc3nc(N)sc3c2C1

InChI Key: InChIKey=DSJQTHADLDMTRA-UHFFFAOYSA-N

Data: 3 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50092170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50092170 (CHEMBL116372 | N*8*,N*8*-Dipropyl-8,9-dihydro-7H-c...) Show SMILES CCCN(CCC)C1COc2ccc3nc(N)sc3c2C1 Show InChI InChI=1S/C16H23N3OS/c1-3-7-19(8-4-2)11-9-12-14(20-10-11)6-5-13-15(12)21-16(17)18-13/h5-6,11H,3-4,7-10H2,1-2H3,(H2,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maastricht Curated by ChEMBL					Assay Description in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]-0437 as radiolig...				J Med Chem 43: 3549-57 (2000) BindingDB Entry DOI: 10.7270/Q2B27W0T
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50092170 (CHEMBL116372 | N*8*,N*8*-Dipropyl-8,9-dihydro-7H-c...) Show SMILES CCCN(CCC)C1COc2ccc3nc(N)sc3c2C1 Show InChI InChI=1S/C16H23N3OS/c1-3-7-19(8-4-2)11-9-12-14(20-10-11)6-5-13-15(12)21-16(17)18-13/h5-6,11H,3-4,7-10H2,1-2H3,(H2,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maastricht Curated by ChEMBL					Assay Description in vitro binding affinity was determined on human Dopamine receptor D3 expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radio...				J Med Chem 43: 3549-57 (2000) BindingDB Entry DOI: 10.7270/Q2B27W0T
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50092170 (CHEMBL116372 | N*8*,N*8*-Dipropyl-8,9-dihydro-7H-c...) Show SMILES CCCN(CCC)C1COc2ccc3nc(N)sc3c2C1 Show InChI InChI=1S/C16H23N3OS/c1-3-7-19(8-4-2)11-9-12-14(20-10-11)6-5-13-15(12)21-16(17)18-13/h5-6,11H,3-4,7-10H2,1-2H3,(H2,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maastricht Curated by ChEMBL					Assay Description in vitro binding affinity was determined on human Dopamine receptor D2L expressed in chinese hamster ovary(CHO) K-1 cells using [3H]spiperone as radi...				J Med Chem 43: 3549-57 (2000) BindingDB Entry DOI: 10.7270/Q2B27W0T
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50092170 (CHEMBL116372 | N*8*,N*8*-Dipropyl-8,9-dihydro-7H-c...) Show SMILES CCCN(CCC)C1COc2ccc3nc(N)sc3c2C1 Show InChI InChI=1S/C16H23N3OS/c1-3-7-19(8-4-2)11-9-12-14(20-10-11)6-5-13-15(12)21-16(17)18-13/h5-6,11H,3-4,7-10H2,1-2H3,(H2,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	148	n/a	n/a	n/a	n/a
University of Maastricht Curated by ChEMBL					Assay Description Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D2L by mitogenesis assay				J Med Chem 43: 3549-57 (2000) BindingDB Entry DOI: 10.7270/Q2B27W0T
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50092170 (CHEMBL116372 | N*8*,N*8*-Dipropyl-8,9-dihydro-7H-c...) Show SMILES CCCN(CCC)C1COc2ccc3nc(N)sc3c2C1 Show InChI InChI=1S/C16H23N3OS/c1-3-7-19(8-4-2)11-9-12-14(20-10-11)6-5-13-15(12)21-16(17)18-13/h5-6,11H,3-4,7-10H2,1-2H3,(H2,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
University of Maastricht Curated by ChEMBL					Assay Description Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D3 by mitogenesis assay				J Med Chem 43: 3549-57 (2000) BindingDB Entry DOI: 10.7270/Q2B27W0T
					More data for this Ligand-Target Pair