BDBM50092231 (4-Phenoxy-phenyl)-quinazolin-4-yl-amine::CHEMBL304760

SMILES: N(c1ccc(Oc2ccccc2)cc1)c1ncnc2ccccc12

InChI Key: InChIKey=RJOICMFRJBMONF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50092231 ((4-Phenoxy-phenyl)-quinazolin-4-yl-amine | CHEMBL3...) Show SMILES N(c1ccc(Oc2ccccc2)cc1)c1ncnc2ccccc12 Show InChI InChI=1S/C20H15N3O/c1-2-6-16(7-3-1)24-17-12-10-15(11-13-17)23-20-18-8-4-5-9-19(18)21-14-22-20/h1-14H,(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
BASF Bioresearch Corporation Curated by ChEMBL					Assay Description Inhibition of tie-2 at 5 uM ATP				Bioorg Med Chem Lett 10: 2167-70 (2001) BindingDB Entry DOI: 10.7270/Q2J38RTH
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50092231 ((4-Phenoxy-phenyl)-quinazolin-4-yl-amine | CHEMBL3...) Show SMILES N(c1ccc(Oc2ccccc2)cc1)c1ncnc2ccccc12 Show InChI InChI=1S/C20H15N3O/c1-2-6-16(7-3-1)24-17-12-10-15(11-13-17)23-20-18-8-4-5-9-19(18)21-14-22-20/h1-14H,(H,21,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	<8	n/a	n/a	n/a	n/a	n/a	n/a
BASF Bioresearch Corporation Curated by ChEMBL					Assay Description Inhibition of p56 Lck tyrosine kinase at 1 mM ATP				Bioorg Med Chem Lett 10: 2167-70 (2001) BindingDB Entry DOI: 10.7270/Q2J38RTH
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50092231 ((4-Phenoxy-phenyl)-quinazolin-4-yl-amine | CHEMBL3...) Show SMILES N(c1ccc(Oc2ccccc2)cc1)c1ncnc2ccccc12 Show InChI InChI=1S/C20H15N3O/c1-2-6-16(7-3-1)24-17-12-10-15(11-13-17)23-20-18-8-4-5-9-19(18)21-14-22-20/h1-14H,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
BASF Bioresearch Corporation Curated by ChEMBL					Assay Description Inhibition of Vascular endothelial growth factor receptor 2 at 5 uM ATP				Bioorg Med Chem Lett 10: 2167-70 (2001) BindingDB Entry DOI: 10.7270/Q2J38RTH
					More data for this Ligand-Target Pair